Nanox.AI HealthCCSng Coding and Reimbursement Guide

Overview

Software analysis of coronary artery calcium from chest CT scans

This guide provides information that may be reported for software analysis of coronary artery calcium from chest CT scans.

The Centers for Medicare and Medicaid Services (CMS) established a new HealthCare Common Procedure Coding System (HCPCS) code G0680 to describe the procedure associated with software analysis of coronary artery calcium and/or aortic valve calcification from chest CT scans effective April 1, 2026.

Private payers and Medicare coverage may differ. It is recommended that providers verify current coverage policies and prior authorization requirements. Please check with your individual payer for their specific coding, coverage, and payment requirements.

Hospital outpatient reimbursement

Effective April 1, 2026

HCPCS code G0680

Status indicator S

APC assignment 1492

                    2026 Medicare national average payment
                    $15.5
                

HCPCS Code	Description	Status Indicator	Ambulatory Payment Classification (APC) Assignment	APC Description	Hospital Outpatient 2026 Medicare National Average Payment
G0680	Detection and quantification of coronary artery calcium and/or aortic valve calcification from algorithmic analysis of computed tomography of the chest with report	S	1492	New Technology Level 1B	Appx. $15.5

Eligible chest CT codes

Eligible Chest CT Codes for Separate G0680 Billing with Nanox.AI HealthCCSng

When an eligible chest CT is performed and billed, qualifying algorithmic analysis and reporting may be billed separately using HCPCS code G0680.

CPT code	Chest CT type	When G0680 May Apply
71250	CT chest / thorax without contrast	Primary eligible code
71271	Low-dose CT lung cancer screening	Primary eligible code
71270	CT chest without and with contrast	Conditionally eligible

Reimbursement calculator

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You’re already performing the chest CTs. Nanox.AI HealthCCSng enables qualifying algorithmic analysis and reporting that can be billed separately under G0680.

Projected 5-yr return $0

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New CAC patients / yr 0

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You’re already performing the chest CTs. Nanox.AI HealthCCSng enables qualifying algorithmic analysis and reporting that can be billed separately under G0680.

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Important information

Notes, sources, and disclaimer

Note

Individual Medicare Administrative Contractors (MACs) and private payers will establish payment amounts for these services, on an individual case basis following review of documentation. A complete description and documentation must be submitted with the claim to support the service provided and medical necessity.

Relative Value Units (RVUs) are used to represent the value of resources needed to perform procedures and services.

Nanox.AI HealthCCSng should be used only in accordance with its FDA-cleared intended use.

Providers remain solely responsible for compliance with all applicable federal and state laws, CMS requirements, payer policies, documentation standards and medical necessity requirements.

* The inclusion of CPT codes in this guide does not guarantee coverage, coding, billing or payment. Providers are responsible for determining whether all applicable billing requirements.

Sources

April 2026 Update of the Hospital Outpatient Prospective Payment System (OPPS) – March 27, 2026. Transmittal 13702
2026 National Physician Fee Schedule Relative Value File April 2026 release updated May 1, 2026.
Medicare Program; Changes to Hospital Outpatient Prospective Payment and Ambulatory Surgical Center Payment Systems and Quality Reporting Programs; Overall Hospital Quality Star Rating: Hospital Price Transparency: and Notice of Closure of a Teaching Hospital and Opportunity To Apply for Available Slots; Final Rule with Comment, Federal Register (90 Fed Reg. No. 225) November 25, 2025, 42 CFR Parts 410, 412, 413, 415, 416, and 419, Addenda A, and B.

Disclaimer

Nano-x Imaging Ltd provides this information for your convenience only. It does not constitute reimbursement or legal advice. The information provided is gathered from third-party sources and is subject to change without notice due to frequently changing laws, rules and regulations. Providers are responsible for decisions relating to coding and reimbursement submissions. Please note that the information in this Guide is subject to change without notice. It is always the health care provider’s responsibility to determine medical necessity and submit appropriate codes, modifiers, and charges for services rendered. Nano-x Imaging Ltd assumes no liability for data contained or not contained herein. Providers should contact their third-party payers for specific information on their coding, coverage, and payment policies. Providers remain solely responsible for compliance with all applicable federal and state laws, CMS requirements, payer policies, documentation standards and medical necessity requirements.